Transcriptomics,Genomics

Dataset Information

34

MiRNA expression profile of human subcutaneous adipose


ABSTRACT: Objective: Potential regulators of adipogenesis include microRNAs (miRNAs), small non-coding RNAs that have been recently shown related to adiposity and differentially expressed in fat depots. However, to date no study is available regarding the relationship of miRNAs expression profile, biological pathway and cellular phenotype during human adipogenesis. Thereby, the aim of this study was to investigate whether miRNA expression profile in human adipocytes is related to adipogenesis and to test whether miRNA profile in human subcutaneous adipose tissue is associated to human obesity and co-morbidities. Keywords: miRNA expression Overall design: subcutaneous fat samples from non-obese (n=6) and obese with (n=9) and without (n=13) Type 2 Diabetes Mellitus (DM-2) women.

INSTRUMENT(S): Agilent-019118 Human miRNA Microarray 2.0 G4470B (Feature Number version)

SUBMITTER: Francisco Jose Ortega  

PROVIDER: GSE18470 | GEO | 2010-05-13

SECONDARY ACCESSION(S): PRJNA118199

REPOSITORIES: GEO

altmetric image

Publications


BACKGROUND: Potential regulators of adipogenesis include microRNAs (miRNAs), small non-coding RNAs that have been recently shown related to adiposity and differentially expressed in fat depots. However, to date no study is available, to our knowledge, regarding miRNAs expression profile during human adipogenesis. Thereby, the aim of this study was to investigate whether miRNA pattern in human fat cells and subcutaneous adipose tissue is associated to obesity and co-morbidities and whether miRNA  ...[more]

Similar Datasets

2010-05-13 | E-GEOD-18469 | ArrayExpress
2017-05-15 | E-GEOD-68885 | ArrayExpress
2015-03-03 | E-GEOD-50574 | ArrayExpress
2012-06-30 | E-GEOD-35012 | ArrayExpress
2015-05-06 | E-GEOD-58622 | ArrayExpress
2011-05-31 | E-GEOD-27949 | ArrayExpress
2011-05-31 | E-GEOD-27912 | ArrayExpress
| GSE24884 | GEO
2014-02-01 | E-GEOD-50489 | ArrayExpress
2015-09-15 | E-GEOD-67024 | ArrayExpress