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Expression data from in vitro polarized-pathogenic Th17 system transfected with YY1 shRNA lentivirus

ABSTRACT: The proportion of pathogenic Th17 (pTh17) cells were significantly higher in RA than that in control individuals and showed a potential relevance with YY1 expression. Increased YY1 expression was observed in pTh17, and the pTh17 differentiation was hampered by YY1 knockdown. We used microarrays to detail the gene expression changes of pTh17 transfected with YY1 shRNA lentivirus and tried to elucidate the potential mechanisms how YY1 can affect pTh17 cell differentiation in RA.

ORGANISM(S): Homo sapiens

PROVIDER: GSE184979 | GEO | 2021/09/30

REPOSITORIES: GEO

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Expression data from in vitro polarized-pathogenic Th17 system transfected with YY1 shRNA lentivirus

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