Genomics

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DNA methylation-based classification of MCD in the human brain


ABSTRACT: Genome wide DNA methylation profiling of human normal and epileptic brain tissue. The Illumina Infinium 850K Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 850.000 CpGs in formalin-fixed paraffin-embedded surgical brain samples. Samples included 316 cases diagnosed with malformations of cortical development (MCD), non-MCD epilepsy or no-epilepsy autopsy controls.

ORGANISM(S): Homo sapiens

PROVIDER: GSE185090 | GEO | 2021/11/30

REPOSITORIES: GEO

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