Lnc-SLC15A1-1 Up-regulates CXCL10/CXCL8 Expression in Endothelial Cells by Sponging MicroRNAs

ABSTRACT: The molecular factors that cause disproportional increase in CVD in the DM/chronic kidney disease (CKD) population are still unknown. HUVESs were treated with high glucose (HG) or HG superimposed uremic toxin indoxyl sulfate (IS). Lnc-SLC15A1-1 was significant different expression between these two condition. HUVECs were transfected with lnc-SLC15A1-1 overexpression vector then microarray was applied to evaluate the downstream regulated gene.

ORGANISM(S): Homo sapiens

PROVIDER: GSE185363 | GEO | 2021/10/06

REPOSITORIES: GEO