KIR+CD8+ and NKG2A+CD8+ T cells are distinct innate-like populations in humans

ABSTRACT: We studied the heterogeneity among human KIR/NKG2A+CD8+ T cells. First, we found that KIRs and NKG2A are expressed on human CD8+ T cells in a mutually exclusive manner. Therefore, we compared KIR+CD8+ and NKG2A+CD8+ T cells in regards to TCR overlap and transcriptomic profiles and demonstrated that KIR+CD8+ and NKG2A+CD8+ T cells are distinct innate-like populations.

ORGANISM(S): Homo sapiens

PROVIDER: GSE185567 | GEO | 2023/02/23

REPOSITORIES: GEO