The role of miR-199a-3p in epithelial to mesenchymal transition of keratinocytes

ABSTRACT: We found that miR-199a-3p expression is decreased in cSCC biopsies and cell lines compared to normal skin biopsies or normal keratinocytes cell. To understand the role lost expression of miR-199a-3p might have in tumorigenesis of keratinocytes, we aimed to fine possible biochemical pathways and possible targets of miR-199a-3p in cSCC. In order do so, we overexpressed miR-199a-3p in cSCC and used microarrays to find global gene expression affected by miR-199a-3p.

ORGANISM(S): Homo sapiens

PROVIDER: GSE186031 | GEO | 2022/11/01

REPOSITORIES: GEO