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The effect of CD153 engagement on the activation of senescence-associated (SA) T cells

ABSTRACT: Advancing age is associated with the increase and accumulation of unique lymphocyte populations. Among them, CD153+ PD-1+ CD4+ T cells (SA-T cells) may underlie the pathogenesis of autoimmune and chronic inflammatory diseases. To assess the possible involvement of CD153 in regulating the cellular function, we performed bulk RNA-seq analysis.

ORGANISM(S): Mus musculus

PROVIDER: GSE186221 | GEO | 2022/09/20

REPOSITORIES: GEO

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