RNA-seq analyses of human ameloblastoma and odontogenic keratocyst

ABSTRACT: Ameloblastoma (AM) is a benign but locally invasive tumor with high recurrence rates. Invasive behavior of the odontogenic tumor results in destruction of the adjacent jawbone and formation of daughter cysts, hindering the complete elimination of cancer cells during surgery. To understand the underlying mechanism of AM invasion, we compared the transcriptome of AM with that of an odontogenic keratocyst (OKC), a dental epithelium-originated cyst with non-invasive characteristics.

ORGANISM(S): Homo sapiens

PROVIDER: GSE186489 | GEO | 2022/05/02

REPOSITORIES: GEO