Project description:To explore the potential functions of ASAP2 in macrophage, we established ASAP2 stable knockdown THP-1 cells and differentiated them into macrophages with PMA (50 ng/ml, 48 hours). Then we performed RNA-sequencing on the macrophages derived from THP-1 with (shASAP2) or without ASAP2 knockdown (shNC) to analyze the enriched functions by ASAP2-correlated genes and differentially expressed genes.

2022-11-08 | GSE217201 | GEO

RNA sequencing of SNRPB2 knockdown in MDA-LM2 cells

Project description:We used RNA sequencing to compare SNRPB2 knockdown cells to mock-transfected controls.

2021-03-30 | GSE160952 | GEO

RNA sequencing on in vitro differentiated WT and GOT1-/- Th17 cells

Project description:Naive CD4+ T cells (CD4+CD25-CD44-CD62L+) were FACS sorted from WT or T cell conditional GOT1-/- C57BL/6 mouse spleen and lymph nodes. Sorted cells were differentiated into Th17 cells in the presence of TGFβ, IL1β, IL6, IL23, anti-IFNγ and anti-IL4. RNA sequencing was then performed on day4 differentiated TH17 cells.

2023-02-02 | GSE215115 | GEO

RNA sequencing of SNRPA1 knockdown in MDA-LM2 cells

Project description:We used RNA sequencing to compare SNRPA1 knockdown cells to mock-transfected controls respectively.

2021-03-30 | GSE160950 | GEO