CUT&RUN of TAF4b and H3K4me3 in E16.5 oocytes

ABSTRACT: Research has shown that Taf4b-deficient female mice display excessive perinatal germ cell death, delayed germ cell cyst breakdown, and increased chromosome asynapsis. Therefore, we hypothesized that TAF4b, as part of TFIID, regulates oogenesis and meiotic gene programs. However, the direct targets of TAF4b have not been thoroughly explored. Therefore, we performed Cleavage Under Targets and Release Using Nuclease (CUT&RUN) in E16.5 mouse oocytes.

ORGANISM(S): Mus musculus

PROVIDER: GSE186991 | GEO | 2022/01/25

REPOSITORIES: GEO