Epigenetic reprogramming of intestinal stemness by dietary arachidonic acid [intestinal organoids]

ABSTRACT: We evaluated the effects of arachidonic acid (AA) on intestinal stem cell regeneration by RNA-seq and found that AA treatment led to strong upregulation of genes that are associated with stem cell reprogramming across the time points. AA elicits a conserved stem cell regeneration program in mouse intestinal organoids.

ORGANISM(S): Mus musculus

PROVIDER: GSE188213 | GEO | 2023/03/01

REPOSITORIES: GEO