The siRNA seed region is divided into two functionally different domains in RNA interference in response to 2´-OMe modifications

ABSTRACT: To investigate effects of siRNA with 2'-O-methyl (2'-Ome) modifications on genome-wide off-targetat, we analyzed gene expression profile of HeLa cells transfected by their siRNAs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE188314 | GEO | 2022/01/11

REPOSITORIES: GEO