A non-canonical R-loop resolving function of PIWIL4 maintains the genomic integrity and leukemic growth of AML cells [PAR-CLIP]

ABSTRACT: PIWIL4 is a RNA binding enzyme required for the resolution of R-loops in AML cells. We examine the RNA associated with PIWIL4 protein in AML cell line THP-1

ORGANISM(S): Homo sapiens

PROVIDER: GSE188383 | GEO | 2022/11/01

REPOSITORIES: GEO