RNAsequencing of plasma cells generated ex vivo upon 2 days of LPS stimulation on WT and Sec22B-KO plasma cells

ABSTRACT: We report RNAseq data obtains from ex vivo generated plasma cell after 2 days of stimulation with LPS. We compare WT plasma cells to Sec22bB-KO plasma cells. Sec22b KO is specific of B cell lineage. We find over 6000 genes differentially regulated between both genotypes. Gene set enrichment analyses (GSEA) revealed that several pathways were significantly different between WT and Sec22bB-KO PCs.

ORGANISM(S): Mus musculus

PROVIDER: GSE188452 | GEO | 2024/10/29

REPOSITORIES: GEO