RNA sequencing of inguinal white adipose tissue from seipin-deficient mice and appropriate controls

ABSTRACT: We generated Bscl2lox/lox mice X ERT2-Adipoq-CRE mice, allowing inducible seipin deletion in adipocytes upon tamoxifen addition (iATSKO). Indeed, a 5-day tamoxifen treatment led to a dramatic decrease in Bscl2 mRNA in the adipose tissue. To study the effects of seipin deficiency in vivo on adipose tissue homeostasis in an unbiased manner, we used 3’-signal recognition particle (SRP) RNA sequencing.

ORGANISM(S): Mus musculus

PROVIDER: GSE188544 | GEO | 2022/01/11

REPOSITORIES: GEO