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Effects of Id1 depletion in TAMs on the genes expression of MC38 cells.

ABSTRACT: We report the application of high-throughput mRNA sequencing to explore the effect of Id1 depletion in TAMs on gene expression of MC38 cells. Different groups of TAMs were isolated from the subcutaneous tumors in Id1f/f or myeloid cell lineage speciﬁc Id1 deficient mice (Id1-Lyz-KO) . MC38 cells were then mixed with two groups of TAMs and be implanted in C57BL/6J mice. CD45- cells were then isolated from the subcutaneous tumors described above to do the transcriptome sequencing.

ORGANISM(S): Mus musculus

PROVIDER: GSE188572 | GEO | 2023/10/15

REPOSITORIES: GEO

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Effects of Id1 depletion in TAMs on the genes expression of MC38 cells.

Project description:We report the application of high-throughput mRNA sequencing to explore the effect of Id1 depletion in TAMs on its gene expression . Different groups of TAMs were isolated from the subcutaneous tumors in Id1f/f or myeloid cell lineage speciﬁc Id1 deficient mice (Id1-Lyz-KO) .

2023-10-15 | GSE200855 | GEO

Single-cell RNAseq of CD45 positive cells in MC38 tumors - Primary irradiated tumors and secondary non-irradiated tumors - Concurrent treatment with anti-PD-L1

Project description:Primary irradiated MC38 tumors and secondary MC38 non-irradiated tumors. Subcutaneous MC38 tumors in C57BL/6 mice Concurrent treatment with anti-PD-L1.

2023-10-15 | E-MTAB-13389 | biostudies-arrayexpress

Heme-TAMs prevent cancer cell apoptosis and drive growth, invasiveness, and metastasis

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2018-08-09 | GSE114533 | GEO

RNA-seq of parental MC38 and anti-PD-1 resistant MC38 subcutaneous tumors

Project description:RNA-seq of parental MC38 and anti-PD-1 resistant MC38 subcutaneous tumors

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Id1 overexpressing BMDC

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The effect of imatinib therapy on tumor associated macrophages (TAMs) in murine gastrointestinal stromal tumor (GIST)

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ID1 and CEBPA coordinate epidermal progenitor cell

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2022-10-14 | GSE215055 | GEO

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