Sex and mutation specific p53 gain-of-function activity in gliomagenesis [ChIP-seq]

ABSTRACT: ChIP-seq analysis of Primary cortical astrocytes harboring a single floxed Trp53 allele harvested from male and female postnatal day one pups, and transduced with mutant p53;IRES GFP followed by CRE recombinase. p53 protein was immunoprecipated from fixed whole chromatin from cells expressing one of three mutants or p53 KO control.

ORGANISM(S): Mus musculus

PROVIDER: GSE188708 | GEO | 2021/11/16

REPOSITORIES: GEO