The role of RPA1 in T cells [spleen]

ABSTRACT: As a single strand DNA binding protein, RPA1 participates in various cellular processes including DNA replication and DNA repair. However, the role of RPA1 in T cells is largely unknown. We generated a mouse model in which RPA1 was specifically deleted in T cells. Through single cell RNA sequencing, we reveal the immune landscape in RPA1 conditional knockout mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE189467 | GEO | 2024/06/15

REPOSITORIES: GEO