Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA sequencing data of 2102EP cells treated with epigenetic agents Quisinostat, JIB-04, Chaetocin, MZ-1, LP99, PRT4165 and GSK343 and DMSO as solvent control

ABSTRACT: Single end 3' RNA sequencing of embryonal carcinoma cell line 2102EP treated with epigenetic agents Quisinostat, JIB-04, Chaetocin, Mz-1, LP99, PRT4165 and GSK343. DMSO was used as solvent control. Cells were treated with the epi-drugs for 16 h.

ORGANISM(S): Homo sapiens

PROVIDER: GSE189472 | GEO | 2022/01/21

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

RNA sequencing data of 2102EP cells treated with epigenetic agents Quisinostat, JIB-04, Chaetocin, MZ-1, LP99, PRT4165 and GSK343 and DMSO as solvent control

Project description:RNA sequencing data of 2102EP cells treated with epigenetic agents Quisinostat, JIB-04, Chaetocin, MZ-1, LP99, PRT4165 and GSK343 and DMSO as solvent control

| PRJNA783199 | ENA

Chaetocin efficacy on Dahl rat

Project description:Transcriptional profiling of left ventricular tissues of Dahl rat with or without treatment of chaetocin Three-condition experiment, Control vs. failing heart, failing heart vs. treatment with chaetocin. 3 samples mixture per each group

2016-04-01 | E-GEOD-66617 | biostudies-arrayexpress

ATAC sequencing data of 2102EP, VM-CUB-1, Caki-1 and DU-145 cells treated with epigenetic agent LAK31 (2102EP additionally: Romidepsin, Quisinostat and MZ-1) and DMSO as solvent control

Project description:ATAC sequencing data of cell lines of urological malignancies treated with epigenetic agents LAK31, Romidepsin, Quisinostat and MZ-1.

2022-09-01 | GSE191184 | GEO

Chaetocin efficacy on Dahl rat

Project description:Transcriptional profiling of left ventricular tissues of Dahl rat with or without treatment of chaetocin

2016-04-01 | GSE66617 | GEO

Identification of genes modulated by JIB-04 in lung cancer cells

Project description:JIB-04 is an inhibitor of Jumonji histone demethylases identified through a cell based screen that measures the reactivation of an epigenetically silenced transgene. The active JIB-04 E-isomer shows selectivity for cancer vs. normal cells affecting both transcriptional patterns and cell viability in a cancer specific manner. H358 lung cancer cells or the patient matched HCC4017 (cancer) vs. HBEC30KT (immortalized normal) lung cell pair were treated with DMSO vehicle or 500nM E-isomer or 500 nM Z-isomer of JIB-04 for 4 h or 24 h and RNA extracted.

2013-07-08 | E-GEOD-46632 | biostudies-arrayexpress

Study the differential gene expression in A375 cells treated with DMSO or XL413 or GSK343 or GSK343 and XL413 combination

Project description:The study evaluated the differential gene expression in A375 cells treated with DMSO when compared to XL413 or GSK343 or GSK343 and XL413 combination using RNA-seq

2022-08-10 | GSE186276 | GEO

Chaetocin Mediated Changes in Gene Expression Profile of GBM Cells

Project description:Chaetocin treatment significantly modulated expression profile of GBM cells such that 373 genes were up and 478 genes were down regulated significantly (FDR<0.05). Genes involved in DNA damage response, reactive oxygen species pathway and cell cycle regulation as well as epithelial to mesenchymal transition are significantly modified by Chaetocin, which render GBM cells much more prone to apoptosis.

2019-02-13 | GSE126462 | GEO

Identification of genes modulated by JIB-04 in lung cancer cells

2013-07-08 | GSE46632 | GEO

Effect of calcipotriol treatment, chaetocin treatment and VDR knockdown on gene expression in BJ cells

Project description:To investigate the effect of calcipotriol treatment, chaetocin treatment and VDR knockdown on gene expression primary normal human fibroblasts, we treated BJ cells with 100 nM calcipotriol for 4 or 24 hours, 50 nM chaetocin for 24 hours, knocked down VDR with si RNA respectively. Then, we performed RNA-seq analysis.

2023-02-11 | GSE224311 | GEO

Illumina Infinium MethylationEPIC BeadChip (850k) data of NCCIT / 2102EP cells deficient for CD24 and parental controls

Project description:Illumina Infinium MethylationEPIC BeadChip (850k) array analysis of DNA methylation of embryonal carcinoma cell lines NCCIT and 2102EP deficient for CD24 and parental cells. CD24 deficiency was genereted by CRISPR/Cas9 method. Three different NCCIT and 2102EP knock out clones were analyzed.

2021-08-01 | GSE176450 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data