Macrophage elastase (MMP12) critically contributes to the development of subretinal fibrosis

ABSTRACT: Macular subretinal fibrosis is the end-stage complication of neovascular age-related macular degeneration (nAMD). RPE/Choroid from control and subretinal fibrosis mice were collected and processed for RNA sequencing (RNA-seq) analysis to investigate the molecular mechanism of subretinal fibrosis.

ORGANISM(S): Mus musculus

PROVIDER: GSE189555 | GEO | 2022/04/13

REPOSITORIES: GEO