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Bromodomain member BRD4 is required for hematopoietic stem cell functions

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Mus musculus

PROVIDER: GSE189836 | GEO | 2023/08/20

REPOSITORIES: GEO

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Bromodomain member BRD4 is required for hematopoietic stem cell functions (scRNA-Seq)

Project description:To investigate the role of BRD4 in normal hematopoiesis, Brd4 conditional KO mouse model was generated. We purified the cKit+ and LSK cells from bone marrow of WT and Brd4 KO mice and performed the single cell RNA-seq to study the molecular changes in each cell population.

2023-08-20 | GSE189835 | GEO

Bromodomain member BRD4 is required for hematopoietic stem cell functions (RNA-Seq)

Project description:To investigate the role of BRD4 in normal hematopoiesis, Brd4 conditional KO mouse model was generated. We purified the Lin-cKit+ cells from bone marrow of WT and Brd4 KO mice and performed the RNA-seq to study the molecular changes in each cell population.

2023-08-20 | GSE189834 | GEO

Bromodomain member BRD4 is required for hematopoietic stem cell functions (CUT&RUN)

Project description:To investigate the role of BRD4 in normal hematopoiesis, Brd4 conditional KO mouse model was generated. We purified the Lin-cKit+ cells from bone marrow of WT and Brd4 KO mice and performed the CUT&RUN to study the histone modification and Brd4 occupancy around genome in HSC/HPCs population.

2023-08-20 | GSE189833 | GEO

Bromodomain member BRD4 is required for hematopoietic stem cell functions (ATAC-Seq)

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Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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Bromodomain protein BRD4 is required for estrogen receptor-dependent transcription and enhancer activation

Project description:This SuperSeries is composed of the SubSeries listed below.

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Project description:This SuperSeries is composed of the SubSeries listed below.

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Project description:This SuperSeries is composed of the SubSeries listed below.

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