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Gene expression by high-throughput sequencing of T47D-MTVL human breast cancer cells upon H1.2 knock-down

ABSTRACT: Gene expression of T47D-MTVL human breast cancer cells expressing Dox-inducible shRNAs against histone H1.2 (H1.2sh).

ORGANISM(S): Homo sapiens

PROVIDER: GSE190158 | GEO | 2023/12/08

REPOSITORIES: GEO

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Project description:Gene expression of T47D-MTVL human breast cancer cells expressing Dox-inducible shRNAs against histone H1X Stable breast cancer-derived cell lines expressing an shRNA against the histone H1X isoforms in response to doxycycline (Dox) were grown for six days in the presence or absence of Dox, and serum-starved for the last 48h for synchronization in G1, in duplicate, and RNA extracted for microarray hybridization. Cell lines used: inducible shRNA against H1X, and random shRNA-expression vector as a control.

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Chromatin-enriched RNAs expression profiling by high-throughput sequencing of T47D-MTVL human breast cancer cells

Project description:Chromatin-enriched RNAs expression of T47D-MTVL human breast cancer cells expressing Dox-inducible shRNAs against multiple histone H1 variants (multiH1sh).

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T47D_MTVL_H1.2sh or T47D_MTVL_controlsh

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