Identification and tracking of alloreactive T cell clones in Rhesus Macaques (RM) through the RM-scTCR-Seq platform

ABSTRACT: T cell receptor clonotype tracking is a powerful tool for interrogating T cell mediated immune processes We apply this method to a Rhesus Macaque model of Graft Versus Host Disease (GvHD), and identify and track in vitro detected alloreactive clonotypes in GvHD target organs and explore their GvHD driven cytotoxic T cell signature.

ORGANISM(S): Macaca mulatta

PROVIDER: GSE190268 | GEO | 2021/12/21

REPOSITORIES: GEO