Mmp-13 deletion in cells of the mesenchymal lineage increases bone mass, decreases endocortical osteoclast number and attenuates the cortical bone loss caused by estrogen deficiency in mice

ABSTRACT: We generated mice with conditional Mmp-13 deletion in Prrx1 expressing cells (Mmp-13dPrrx1) and compared the effect of estrogen deficiency on their bone phenotype to that of control littermates (Mmp-13f/f)

ORGANISM(S): Mus musculus

PROVIDER: GSE191214 | GEO | 2022/06/01

REPOSITORIES: GEO