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Microarray Analysis of Temperature-induced Transcriptome of Streptococcus suis serotype 2

ABSTRACT: Streptococcus suis serotype 2 (SS2) is able to cause human infections ranging from superficial wounded skin infections to severe invasive infections such as meningitis and streptococcal toxic shock-like syndrome (STSLS). During its infection cycle, SS2 must acclimatize itself to temperature shift. Herein, a whole-genome DNA microarray was used to investigate the global transcriptional regulation of an invasive SS2 strain grown to late-exponential phase at 29 or 40°C relative to 37°C. The detecting differentially regulated genes included those encoding virulence factors, antigenic proteins, ABC transporters and unknown functions. Our data provided a global profile of gene transcription induced by temperature alteration and shed light on some unforeseen lines for further pathogenesis investigation.

ORGANISM(S): Streptococcus suis 05ZYH33

PROVIDER: GSE19215 | GEO | 2009/12/02

SECONDARY ACCESSION(S): PRJNA120833

REPOSITORIES: GEO

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