TRF & tiRNA sequencing of breast cancer tissue samples and matched non-tumor adjacent tissues

ABSTRACT: Purposes: To investigate the biological function of tRF in breast cancer by tRF and tiRNA sequencing Methods: Breast cancer tissue samples and matched non-tumor adjacent tissues were obtained from five patients. Small RNA sequencing was performed on Illumina NexSeq instrument Results: If P ≤ 0.05, fold change ≥ 2 as the cut off, there were 3 up-regulated tRFs & tiRNAs and 13 down-regulated tRFs & tiRNAs. Conclusions:There were 3 up-regulated tRFs & tiRNAs and 13 down-regulated tRFs & tiRNAs in breast cancer tissue samples and matching adjacent tissue samples

ORGANISM(S): Homo sapiens

PROVIDER: GSE192737 | GEO | 2022/01/01

REPOSITORIES: GEO