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Effects of doxorubicin on miRNA expression in tumor cell small extracellular vesicles

ABSTRACT: To examine the changes of miRNA in the small extracellular vesicles of breast cancer cells receiving DOX chemotherapy. Human breast cancer cells (MDA-MB-231 cells) were cultured with exorcism-free serum, and treated with DOX. After 24h, cell supernatant was collected and small extracellular vesicles were extracted by ultra-fast centrifugation method, and miRNA content in small extracellular vesicles was obtained for high-throughput miRNA sequencing.

ORGANISM(S): Homo sapiens

PROVIDER: GSE192763 | GEO | 2025/09/24

REPOSITORIES: GEO

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