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A6A-seq: N6-allyladenosine-based cellular messenger RNA metabolic labelling and sequencing

ABSTRACT: In this work, we applied a6A to label and sequence cellular mRNA in an immunoprecipitation-free and mutation-based manner, termed a6A-seq. a6A-seq was utilized to study the change of cellular gene expression profile under a methionine-free stressed condition. Compared with regular RNA-seq, a6A-seq could more sensitively detect the level change of newly synthesized mRNAs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE192818 | GEO | 2021/12/31

REPOSITORIES: GEO

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N6-methyladenosine Modulates Messenger RNA Translation Efficiency

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