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Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and Elf4fl/fl-Villin-Cre Livers Transcriptomes

ABSTRACT: Conclusion: Elf4fl/fl-Villin-Cre mice are more sensitive to alcohol induced liver steatosis

ORGANISM(S): Mus musculus

PROVIDER: GSE192923 | GEO | 2022/05/18

REPOSITORIES: GEO

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Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and Elf4fl/fl-Villin-Cre distal colon Transcriptomes

Project description:Conclusion: Elf4fl/fl-Villin-Cre mice are more sensitive to Dextran sulfate (DSS) induced colon tumorigenesis

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Single-cell analysis of Villin-Cre;Apc min;Lef1 fl/fl (VApcMinL) and ApcMin intestinal adenoma cells at the age of 11 wks

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Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and Elf4fl/fl-Villin-Cre Livers Transcriptomes

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RNA-seq of WT, ELF4-/- CACO2 and Elf4fl/fl-Villin-Cre Livers Transcriptomes

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Next Generation Sequencing Facilitates Quantitative Analysis of Il17ra villin cre -/+ colon transcriptomes at day 10 post C. rodentium infection

Project description:We report analysis of colonic transcriptome in gut epithelial cells specific deficient mouse (Il17ra villin cre +) and littermate control mouse (Il17ra villin cre -) infected with Citrobater rodentium (C. rodentium) for 10 days. We found RNA-seq data show Nox family genes and defensin genes are downregulated in Il17ra villin cre + mice. It is interestingly Tnfsf13 was also downregulated in Il17ra villin cre + mice. These genes expressions were confirmed by qRT–PCR validation was performed using TaqMan assays. Finally, this study provides first detailed analysis of C. rodentium infected colonic transctiptome in Il17ra villin cre + mice, with biologic replicates, generated by RNA-seq technology.

2020-12-08 | GSE160157 | GEO

Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and Elf4fl/fl-Villin-Cre distal colon Transcriptomes

Project description:Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and Elf4fl/fl-Villin-Cre distal colon Transcriptomes

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Gene expression data from mouse colon. AOM+DSS induced colitis. INSR fl/fl mice or villin-CRE INSR-/- mice

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RNA-seq of WT, ELF4-/- CACO2 and Elf4fl/fl-Villin-Cre Livers Transcriptomes

Project description:This SuperSeries is composed of the SubSeries listed below.

2022-05-18 | GSE192924 | GEO

Next Generation Sequencing Facilitates Quantitative Analysis of Runx2fl/fl and Gli1-CreERT2;Runx2fl/fl Incisor Transcriptomes

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2020-03-05 | GSE146332 | GEO

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