Genomics

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Arhgdia regulates disease tolerance in IAV-infected epithelial cells


ABSTRACT: When challenged with an invading pathogen, host defense mechanisms are engaged to eliminate the pathogen (resistance) and limit tissue damage that results from host-pathogen interactions (disease tolerance). We identified Arhgdia as a driver of the molecular disease-tolerance response in epithelial cells. The effect of Arhgdia on disease tolerance and resistance was evaluated at early stages of influenza A virus (IAV) infection. Our observations indicates that Arhgdia has an effect on disease tolerance during IAV infection.

ORGANISM(S): Mus musculus

PROVIDER: GSE193160 | GEO | 2022/12/27

REPOSITORIES: GEO

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