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Thyroidal gene expression changes in tamoxifen inducible Foxe1 knockout mouse at two weeks post-treatment

ABSTRACT: To directly examine the role of Foxe1 in the adult thyroid we generated a model of tamoxifen-inducible Cre mediated Foxe1 deletion in mice of C57BL/6J background (Foxe1flox/flox/Cre). Tamoxifen (0.05g/kg) was administered intraperitoneally to Foxe1flox/flox/Cre mice or Cre control mice aged 6-8 weeks, once daily for five consecutive days. Thyroids were harvested two weeks post-treatment, total RNA extracted and transcriptomic analysis performed using Clariom S Mouse arrays.

ORGANISM(S): Mus musculus

PROVIDER: GSE193441 | GEO | 2022/10/01

REPOSITORIES: GEO

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Tamoxifen-induced Ghr deletion in WT mouse prostates

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