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Human gene expression microarray analysis in CEM cells overexpressing HTLV-1 Rex

ABSTRACT: HTLV-1 is an onco-retrovirus that infects human T cells and causes poor prognosis leukaemia/lymphoma, ATL. The viral RNA binding protein, Rex, intervenes in host cell regulation of gene expression, splicing and translation mechanisms to promote viral particle replication, but the detailed mechanism of its function has not been elucidated. In the present study, we stably overexpressed HTLV-1 Rex in the human T-cell-derived cell line, CEM, and investigated effect of Rex on gene expression profiles in CEM cells by gene expression microarray analysis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE193576 | GEO | 2022/03/03

REPOSITORIES: GEO

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