Telomere shortening is associated with over-expression of subtelomeric genesin thyroid tumors.

ABSTRACT: To determine whether telomere shortening in thyroid tumors delineates gene expression of subtelomeric regions, we performed RNA sequencing in a set of tumors (n = 15) and compare gene expression profiles of subtelomeric and non-subtelomeric genes between short telomere tumors and normal telomere tumors. We defined as subtelomeric genes, those located within the 5 megabase windows (Mb) adjacent to the telomeres.

ORGANISM(S): Homo sapiens

PROVIDER: GSE193623 | GEO | 2022/08/24

REPOSITORIES: GEO