Isoform switching events in Barrett's Esophagus and esophageal adenocarcinoma

ABSTRACT: Global isoform switching in esophageal adenocarcinoma (EAC) has not been previously characterized. This form of alternative splicing has recently been recognized as highly prevalent in multiple other cancers. In this study, isoform switch analysis was performed using next generation sequencing of RNA isolated from patient tissues across a continuum of histopathologies, ranging from low risk Barrett’s esophagus (BE) to BE with dysplasia and EAC. Patients were stratified based on histopathology.

ORGANISM(S): Homo sapiens

PROVIDER: GSE193946 | GEO | 2022/08/17

REPOSITORIES: GEO