Transcriptomics

Dataset Information

0

I-SPY2-990 mRNA/RPPA Data Resource: mRNA component


ABSTRACT: The I-SPY2-990 mRNA/RPPA Data Resource contains gene expression and clinical data for 987 patients from 10 arms of the neoadjuvant I-SPY2 TRIAL for aggressive early stage breast cancer [210 Control (Ctr); 71 veliparib/carboplatin (VC); 114 neratinib (N); 93 MK2206; 106 ganitumab; 93 ganetespib; 134 trebananib; 52 TDM1/pertuzumab(P); 44 H/P; 69 pembrolizumab (pembro)]. All 987 patients have pretreatment full transcriptome expression data on over ~19,000 genes assayed on Agilent 44K. Clinical data includes HR, HER2 and MP status, response (pCR or no pCR), and treatment arm. The ISPY2-990 mRNA/RPPA Data Resource also includes normalized pre-treatment LCM-RPPA data for 139 key signaling proteins/phosphoproteins in cancer for 736 patients (see companion GEO record GSE196093 for data and details).

ORGANISM(S): Homo sapiens

PROVIDER: GSE194040 | GEO | 2022/05/25

REPOSITORIES: GEO

Similar Datasets

2022-05-25 | GSE196093 | GEO
2022-05-25 | GSE196096 | GEO
| PRJNA803240 | ENA
| PRJNA803248 | ENA
| PRJNA798787 | ENA
2014-12-31 | GSE55830 | GEO
2015-09-09 | E-GEOD-72795 | biostudies-arrayexpress
2015-09-09 | GSE72795 | GEO
2012-10-22 | E-GEOD-36327 | biostudies-arrayexpress
2024-03-19 | PXD047072 | Pride