Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Long-term culture-expanded alveolar macrophages restore their full epigenetic identity after transfer in vivo

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Mus musculus

PROVIDER: GSE194144 | GEO | 2022/01/23

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Long-term culture-expanded alveolar macrophages restore their full epigenetic identity after transfer in vivo

Project description:Long-term culture-expanded alveolar macrophages restore their full epigenetic identity after transfer in vivo

| PRJNA799301 | ENA

CEACAM1 is a novel culture-compatible surface marker of expanded long-term reconstituting hematopoietic stem cells.

Project description: Not available

| S-EPMC9631550 | biostudies-literature

Long Term Ex Vivo Culture and Live Imaging of Drosophila Larval Imaginal Discs.

Project description: Not available

| S-EPMC5042436 | biostudies-literature

Long-term culture of alveolospheres

Project description:iPSC derived AEC2 cells for independent validation of stable SFTPCtdTomato+ outgrowth by scRNA-seq using iPSCs

2019-09-24 | GSE137799 | GEO

Rapamycin enhances long-term hematopoietic reconstitution of ex vivo expanded mouse hematopoietic stem cells by inhibiting senescence.

Project description: Not available

| S-EPMC3877183 | biostudies-literature

Long-Term Culture of Distal Airway Epithelial Cells Allows Differentiation Towards Alveolar Epithelial Cells Suited for Influenza Virus Studies.

Project description: Not available

| S-EPMC6085545 | biostudies-literature

Ex vivo expanded human 3D Nephrospheres engraft long term and repair chronic renal injury in mice

Project description:End-stage renal disease is a worldwide epidemic requiring renal replacement therapy. Harvesting tissue from failing kidneys and autotransplantation of expanded committed progenitors giving rise to renal parenchyma could theoretically allow for the restoration of kidney function delaying or preventing the need for dialysis or a renal allograft. Here we utilized healthy and end-stage human adult kidneys to robustly expand proliferative kidney epithelial cells and establish 3D-kidney epithelial cultures termed nephrospheres (nSPH). Formation of nephrospheres recapitulates renal developmental programs to reestablish renal identity and revitalize renal epithelia in primary cultures. Transplantation into NOD/SCID mice show that 3D-nSPH restore self-organogenetic properties lost in adherent cultures, allowing in turn efficient engraftment and long-term survival as tubular structures and demonstrating self-organization as critical to prolonged in vivo cell survival. Moreover, long-term tubular engraftment of human nSPH proved to be functionally beneficial in murine models of chronic kidney disease. Remarkably, in vitro, nSPH inhibited pro-fibrotic collagen production in cultured fibroblasts via paracrine modulation of STAT6/IL13 while in vivo, transplanted nSPH induced transcriptional signatures of proliferation and a release from the quiescent state in host tubules potentially re-activating endogenous regeneration. These data support the use of human nSPH for autologous renal cell therapy.

2019-12-03 | GSE141257 | GEO

Long-term culture of alveolospheres

Project description:Long-term culture of alveolospheres

| PRJNA573090 | ENA

Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process.

Project description: Not available

| S-EPMC8082824 | biostudies-literature

HeLa and U2OS long term culture adhesion isolations

Project description:Integrin adhesion complexes have been previously isolated and analysed by mass-spectrometry from cells largely spread on matrix proteins over a couple of hours. Here we wished to determine the composition of adhesion complexes from cells cultured for 72 hours under standard cell culture conditions and identify which integrin heterodimers are utilised under these conditions.

2019-06-03 | PXD008645 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data