Retrograde movements determine effective stem cell numbers in intestinal crypts

ABSTRACT: Our goal was to compare the transcriptomic profile of lgr5+ high, medium and low cells (corresponding to centre, border and >3 row in crypts) between small and large intestine in mice. We observed differences in the transcriptional profile between centre and border Lgr5+ cells within small and large intestinal crypts and more profound differences between the two intestinal sites.

ORGANISM(S): Mus musculus

PROVIDER: GSE194250 | GEO | 2022/04/20

REPOSITORIES: GEO