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Analysis of BTLA regulated transcripts in human B and CD4+ T cells

ABSTRACT: Purified B or CD4+ T cells were analyzed for transcriptional changes induced by the BTLA inhibitory receptor. BTLA receptors were activated using anti-human BTLA coupled to microbeads. Gene expression was analyzed using Nanostring

ORGANISM(S): Homo sapiens

PROVIDER: GSE194314 | GEO | 2022/01/28

REPOSITORIES: GEO

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Expression data from FACS-sorted CD8+BTLA+ vs CD8+BTLA- Human Tumor-infiltrating Lymphocytes in Metastatic Melanoma

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Project description:The intestinal microbiome was examined from fecal pellets of animals with genetic targeting of the BTLA inhibitory receptor and the TNFR superfamily member HVEM, or in animals treated with agonist antibodies specific for BTLA.

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Analysis of BTLA regulated transcripts in human B and CD4+ T cells

Project description:Analysis of BTLA regulated transcripts in human B and CD4+ T cells

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RNAseq analysis of anti-BTLA vs control treated anti-CD3 stimulated mouse T cells or IgM stimulated mouse B cells

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