Project description:We have identified HHEX as an oncogene to promote proliferation in colorectal cancer. To elucidate the potential mechanism of HHEX in colorectal cancer, RNA-seq analysis was performed in HCT116 cells to analyze differential expressed genes after HHEX knockdown.
Project description:ChIP-seq on human HCT116 For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
Project description:ZFX ChIP-seq on human HCT116 For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
Project description:To investigate the role of HHEX in regulating human pancreatic endoderm differentiation, we knocked down the HHEX gene in 585A1 cell line-derived pancreatic endoderm cells by siRNA. We then performed gene expression profiling analysis using data obtained from RNA-seq of the 3 cell samples.
Project description:To test if CDK8 acts directly at HIF1A target genes, we performed ChIP-seq experiments in HCT116 cells under normoxic and hypoxic conditions. ChIP-seq for CDK8 versus Input under normoxia and 24hrs hypoxia (1% O2).
