Transcriptomics

Dataset Information

Expression data from cancer associated fibroblasts (CAFs) treated with OSM


ABSTRACT: The cytokine Oncostatin M (OSM) promotes cancer progression by acting as central node for multicellular interactions between cancer cells and surrounding stromal cells. OSM is mainly secreted by myeloid cells and the oncostatin M receptor (OSMR) is expressed by cancer cells and cancer associated fibroblasts (CAFs), among others. To understand the effect of OSM in CAFs, a small and well-annotated Clariom S gene microarray was performed in CAF-173 cells cultured in 3D spheroids and treated with OSM or vehicle (PBS).

ORGANISM(S): Homo sapiens

PROVIDER: GSE195775 | GEO | 2022/02/02

REPOSITORIES: GEO

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