Atypical mitotic DNA synthesis sequencing (MiDAS-seq) in U2OS cells depleted for RAD51

ABSTRACT: DNA replication stress is an established driver of cancer-associated chromosomal rearrangements. Replication stress perturbs the duplication of late-replicating loci and activates a mitotic DNA repair pathway (termed MiDAS) for completion of replication. We here investigated RAD51-independent MiDAS.

ORGANISM(S): Homo sapiens

PROVIDER: GSE196278 | GEO | 2022/06/27

REPOSITORIES: GEO