Dataset Information


Genetic Analysis of Variation in Transcription Factor Binding in Yeast

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

INSTRUMENT(S): Illumina Genome Analyzer (Saccharomyces cerevisiae)

SUBMITTER: Wei Zheng  

PROVIDER: GSE19636 | GEO | 2010-02-18



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Genetic analysis of variation in transcription factor binding in yeast.

Zheng Wei W   Zhao Hongyu H   Mancera Eugenio E   Steinmetz Lars M LM   Snyder Michael M  

Nature 20100317 7292

Variation in transcriptional regulation is thought to be a major cause of phenotypic diversity. Although widespread differences in gene expression among individuals of a species have been observed, studies to examine the variability of transcription factor binding on a global scale have not been performed, and thus the extent and underlying genetic basis of transcription factor binding diversity is unknown. By mapping differences in transcription factor binding among individuals, here we present  ...[more]

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