Genomics

Dataset Information

16

Genetic Analysis of Variation in Transcription Factor Binding in Yeast


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

INSTRUMENT(S): Illumina Genome Analyzer (Saccharomyces cerevisiae)

SUBMITTER: Wei Zheng   

PROVIDER: GSE19636 | GEO | 2010-02-18

SECONDARY ACCESSION(S): GSE19634GSE19635PRJNA122523

REPOSITORIES: GEO

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Publications

Genetic analysis of variation in transcription factor binding in yeast.

Zheng Wei W   Zhao Hongyu H   Mancera Eugenio E   Steinmetz Lars M LM   Snyder Michael M  

Nature 20100317 7292


Variation in transcriptional regulation is thought to be a major cause of phenotypic diversity. Although widespread differences in gene expression among individuals of a species have been observed, studies to examine the variability of transcription factor binding on a global scale have not been performed, and thus the extent and underlying genetic basis of transcription factor binding diversity is unknown. By mapping differences in transcription factor binding among individuals, here we present  ...[more]

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