PLK inhibitors identified by high content phenotypic screening promote maturation of human iPSC-derived cardiomyocytes

ABSTRACT: We performed RNA-Seq analysis of human pluripotent stem cells derived cardiomyocytes (hPSC-CMs) which were treated with Centrinone or Volasertib for 14 days to investigate the moleclular mechanism of inhibiting L-type calcium channel (LTCC) to promote cardiomyocyte proliferation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE197835 | GEO | 2022/03/06

REPOSITORIES: GEO