Transcriptomics

Dataset Information

0

Bulk RNA-seq of Normal and Doxorubicin-Induced Senescent HCA2 cells


ABSTRACT: Purpose: Use RNA-seq strategy to characterize the PD-L1 correlated genes in sorted PD-L1 negative and positive doxorubicin-induced senescent and normal human foreskin fibroblasts HCA2 cells to identify the upstream transcriptional network for regulating heterogeneous PD-L1 expression in senescent cells. Methods: Early passaged normal HCA2 cells and senescent HCA2 cells induced by 24 hours of 100 nM doxorubicin treatment were utilized for the preparation of bulk RNA-seq libraries. Among the senescent cells, PD-L1 positive and negative cells were separated by FACSorting.

ORGANISM(S): Homo sapiens

PROVIDER: GSE198396 | GEO | 2022/08/27

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2024-02-14 | GSE225286 | GEO
2024-02-14 | GSE225285 | GEO
2019-10-08 | GSE138508 | GEO
2021-07-14 | GSE157284 | GEO
2012-07-09 | E-GEOD-39204 | biostudies-arrayexpress
| PRJNA272776 | ENA
2018-05-24 | GSE107621 | GEO
2018-05-24 | GSE107620 | GEO
2024-09-23 | GSE223509 | GEO
2015-05-01 | E-GEOD-65041 | biostudies-arrayexpress