Mesenchymal stromal cells-derived small extracellular vesicles affect T-lymphocytes mRNA expression

ABSTRACT: In the current research, we further study the immune-modulatory effect of bmMSCs on T cells, by mRNA sequencing of activated T cells co-cultured with bmMSC-sEVs. Methods: activated T lymphocytes were cocultured with and without bmMSC derived sEVs. mRNA profiling was performed using the QIAGEN Illumina sequencing platform. IPA® software, KEGG pathway, GSEA and STRING database were applied to analyze pathway networks and biological functions of the differentially expressed genes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE198738 | GEO | 2025/03/01

REPOSITORIES: GEO