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Region specific astrocyte response to mutant GFAP in Alexander disease model mice during postnatal development.

ABSTRACT: Gene expression analysis was performed in Gfap+/+, Gfap+/R236H, and mGFAPTg170-2 transgenic mice, using the Aldh1l1-eGFP-L10a transgenic line (JD130) to isolate translating ribosomes and purify astrocyte specific transcripts for RNAseq.

ORGANISM(S): Mus musculus

PROVIDER: GSE198817 | GEO | 2023/01/17

REPOSITORIES: GEO

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Genetic modifiers of GFAP expression in mouse models of Alexander disease

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