TREM2 shapes myeloid cell activations in trauma- and autoimmune-mediated neurodegeneration

ABSTRACT: TREM2 signaling in myeloid cells functions as a major pathology-induced immune signaling hub in trauma- and autoimmune-mediated neurodegeneration. Here we compared the influence of TREM2 signaling on single-cell transcriptional profiles of mouse myeloid populations during the pathologies of spinal cord injury (SCI) and multiple sclerosis (MS) models.

ORGANISM(S): Mus musculus

PROVIDER: GSE198852 | GEO | 2023/06/06

REPOSITORIES: GEO