RNA-seq analysis of Vitamin K2 treated WT worms

ABSTRACT: We used RNA-seq analysis to identify changes in gene expression occurring in the worms treated with VK2, and based on these sequencing data, more than fifteen hundred genes were identified as up-regulated by as much as 1.5 times subsequent to VK2 treatment. These differentially expressed genes were analyzed for pathway and gene ontology (GO) enrichment, which indicated that the genes influenced by VK2 treatment were enriched in several significant signaling pathways, including longevity, stress resistance, peroxisome, and fat metabolism pathways.

ORGANISM(S): Caenorhabditis elegans

PROVIDER: GSE199145 | GEO | 2022/03/25

REPOSITORIES: GEO