Transcriptomics

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Human OTULIN haploinsufficiency impairs cell-intrinsic immunity to staphylococcal α-toxin


ABSTRACT: We performed single-cell RNA sequencing (scRNASeq) on cryopreserved peripheral blood mononuclear cells (PBMCs) of healthy controls and OTULIN haploinsufficient patients in order to clarify the perturbation, if any, of cellular phenotypes in various leukocyte subsets in vivo at basal state attributable to OTULIN haploinsufficiency.

ORGANISM(S): Homo sapiens

PROVIDER: GSE199445 | GEO | 2023/04/01

REPOSITORIES: GEO

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