Minicircle-derived iPS cells - Affymetrix Data

ABSTRACT: Owing to the risk of insertional mutagenesis, viral transduction has been increasingly replaced by nonviral methods to generate induced pluripotent stem (iPS) cells. We report the use of ‘minicircle’ DNA, a vector type that is free of bacterial DNA and capable of high expression in cells. Here we use a single minicircle vector to generate transgene-free iPSCs from adult human adipose stem cells. (Note: Our Nature Methods publication included analysis of array data from GSM378832 (Foreskin), GSM378833-GSM378838 (JT-iPSC), and GSM378817-GSM378820 (H1, H7, H9, H13, H14) in conjunction with this series).

ORGANISM(S): Homo sapiens

PROVIDER: GSE20033 | GEO | 2010/02/01

SECONDARY ACCESSION(S): PRJNA124121

REPOSITORIES: GEO